Cov qog nqaij hlav loj hauv cov miv - Cov tsos mob, kev kho mob thiab kev kwv yees

Zoo Siab

• Dab tsi yog mast cell qog hauv miv
• Hom feline mast cell qog
• Cutaneous mast cell qog
• qog nqaij hlav cancer ntawm lub cev
• Cov tsos mob ntawm mast cell qog hauv miv
• Cov tsos mob ntawm cov qog nqaij hlav qog nqaij hlav hauv cov miv
• Cov tsos mob ntawm cov qog nqaij hlav hauv lub cev visceral hauv miv
• Kev kuaj mob ntawm feline mast cell tumor
• Kev kuaj mob ntawm cutaneous mast cell qog hauv miv
• Kev kuaj mob ntawm visceral mast cell qog hauv miv
• Kev kho mob qog noj ntshav mast hauv miv
• Kev kho mob ntawm cov qog nqaij hlav qog nqaij hlav hauv cov miv
• Kev kho mob qog nqaij hlav qog noj ntshav hauv cov miv

Cov qog nqaij hlav loj hauv cov miv tuaj yeem nthuav tawm hauv ob hom sib txawv: tawv nqaij thiab tawv nqaij. Cutaneous mast cell tumor yog qhov nquag thiab yog hom thib ob mob qog noj ntshav ntau nyob hauv miv. Cov qog nqaij hlav qog noj ntshav hauv lub cev tshwm sim feem ntau hauv tus hnoos qeev, txawm hais tias nws tuaj yeem tshwm sim hauv lwm qhov chaw, xws li txoj hnyuv.

Kev kuaj mob yog ua los ntawm cytology lossis kuaj lub cev thaum muaj cov qog nqaij hlav ntawm cov tawv nqaij, thiab los ntawm cytology, kuaj ntshav thiab kuaj mob hauv cov qog nqaij hlav hauv lub cev. Kev kho yog los ntawm kev phais hauv ob qho tib si, txawm hais tias qee yam ntawm cov qog nqaij hlav qog nqaij hlav hauv lub cev nws tsis tau qhia, siv tshuaj kho mob thiab tshuaj txhawb nqa txhawm rau txhim kho lub neej zoo ntawm cov miv nrog qog nqaij hlav qog noj ntshav. Txuas ntxiv nyeem kab ntawv PeritoAnimal no kom paub ntau ntxiv txog mast cell qog, nws cov tsos mob, kev kho mob thiab kev kwv yees.

Dab tsi yog mast cell qog hauv miv

Mastocytoma yog ib hom qog uas tuaj yeem cuam tshuam rau miv uas muaj a exaggerated mast cell sib npaug. Mast cells yog cov cell uas pib hauv pob txha pob txha los ntawm hematopoietic ua ntej thiab tuaj yeem pom ntawm daim tawv nqaij, cov ntaub so ntswg sib txuas, lub plab zom mov, thiab ua pa.

Yog tiv thaiv hlwb thawj kab tawm tsam cov kab mob sib kis thiab lawv cov granules muaj cov tshuaj uas ua kom muaj kev tsis haum thiab ua xua, xws li histamine, TNF-α, IL-6, proteases, thiab lwm yam.

Thaum cov qog nqaij hlav ntawm cov cell no tshwm sim, cov tshuaj muaj nyob hauv lawv cov granules raug tso tawm hauv txoj kev tsis txaus ntseeg, ua rau cov teebmeem hauv cheeb tsam lossis cov txheej txheem uas tuaj yeem coj mus rau ntau yam kev kuaj mob sib txawv nyob ntawm lawv qhov chaw nyob.

Hom feline mast cell qog

Hauv miv, cov qog nqaij hlav hauv lub cev tuaj yeem ua rau tawv nqaij, thaum nyob ntawm daim tawv nqaij; los yog visceral, thaum nyob rau sab hauv viscera.

Cutaneous mast cell qog

Nws yog tus mob qog noj ntshav thib ob nquag heev hauv miv thiab plaub ntawm tag nrho cov qog nqaij hlav hauv miv. Siamese miv zoo li feem ntau yuav raug kev txom nyem los ntawm cov qog nqaij hlav ntawm tes. Lawv muaj nyob ob txoj kev ntawm cov tawv nqaij ntawm cov tawv nqaij mast cell raws li lawv cov yam ntxwv keeb kwm:

• mastocytosis: tshwm sim feem ntau ntawm cov miv muaj hnub nyoog 9 xyoos thiab faib ua daim ntawv me me (feem ntau nquag thiab muaj txiaj ntsig, txog li 90% ntawm cov neeg mob) thiab daim ntawv nthuav tawm (ntau ntxiv ua phem, nkag mus thiab ua rau kis loj).
• Histiocytic: Muaj nyob nruab nrab ntawm 2 thiab 10 xyoos.

qog nqaij hlav cancer ntawm lub cev

Cov qog nqaij hlav mast no tuaj yeem pom hauv cov kab mob parenchymal zoo li:

• Tus po (feem ntau nquag).
• Txoj hnyuv me.
• Mediastinal lymph nodes.
• Mesenteric lymph nodes.

Tshwj xeeb tshaj yog cuam tshuam rau cov laus laus ntawm cov 9 thiab 13 xyoos vajtswv

Cov tsos mob ntawm mast cell qog hauv miv

nyob ntawm seb hom twg feline mast cell qog, cov tsos mob yuav txawv, raws li peb yuav pom hauv qab no.

Cov tsos mob ntawm cov qog nqaij hlav qog nqaij hlav hauv cov miv

Cov qog nqaij hlav ntawm daim tawv nqaij hauv miv tuaj yeem yog ib leeg lossis ntau pawg (20% ntawm cov neeg mob). Lawv tuaj yeem pom ntawm lub taub hau, caj dab, hauv siab lossis nqua, ntawm lwm tus.

Suav nrog nodules uas feem ntau yog:

• Txhais.
• 0.5-3 cm nyob rau hauv lub cheeb.
• Tsis pigmented los yog liab dawb.

Lwm tus cov tsos mob uas tuaj yeem tshwm sim hauv thaj tsam qog yog:

• Erythema.
• Mob ulceration.
• Tsis tu ncua khaus.
• Kev raug tus kheej.
• Kev mob.
• Subcutaneous edema.
• Cov tshuaj tiv thaiv anaphylactic.

Histiocytic mast cell nodules feem ntau ploj tawm ntawm tus kheej

Cov tsos mob ntawm cov qog nqaij hlav hauv lub cev visceral hauv miv

Cov miv nrog cov qog nqaij hlav hauv lub cev pom cov cim qhia ntawm kab mob, zoo li:

• Ntuav.
• Kev nyuaj siab.
• Anorexia.
• Poob phaus.
• Raws plab.
• Hyporexia.
• Ua pa nyuaj yog tias muaj cov pleural tso tawm.
• Splenomegaly (ua rau cov leeg loj zuj zus).
• Ascites.
• Hepatomegaly (daim siab ua haujlwm loj).
• Anemia (14-70%).
• Mastocytosis (31-100%).

Thaum miv nthuav qhia kev hloov hauv tus po, xws li kev nthuav dav, nodules, lossis kev koom nrog hauv nruab nrog cev, thawj qhov uas yuav xav txog yog qog nqaij hlav qog noj ntshav.

Kev kuaj mob ntawm feline mast cell tumor

Kev kuaj mob yuav nyob ntawm hom qog nqaij hlav qog noj ntshav uas tus kws kho tsiaj xav tias tus miv tuaj yeem raug kev txom nyem los ntawm.

Kev kuaj mob ntawm cutaneous mast cell qog hauv miv

Cov qog nqaij hlav ntawm cov tawv nqaij ntawm cov miv tau xav tias yog lub ntsej muag nrog cov yam ntxwv tau piav qhia saum toj no, tau lees paub los ntawm a cytology lossis biopsy.

Histicitic mast cell qog yog qhov nyuaj tshaj plaws los kuaj mob los ntawm cytology vim nws cov yam ntxwv ntawm cov cellular, tsis paub meej thiab muaj cov qog lymphoid.

Nws yuav tsum raug coj mus rau hauv tus account tias, hauv feline eosinophilic granuloma, mast cells kuj tseem tuaj yeem tshwm sim, uas tuaj yeem ua rau kev kuaj mob tsis raug.

Kev kuaj mob ntawm visceral mast cell qog hauv miv

O kev kuaj mob sib txawv ntawm feline visceral mast cell qog, tshwj xeeb tshaj yog ntawm tus spleen, suav nrog cov hauv qab no:

• Splenite.
• Accessory tus po.
• Hemangiosarcoma kev kho mob.
• Nodular hyperplasia.
• Lymphoma.
• Myeloproliferative kab mob.

Ntshav suav, kuaj ntshav biochemistry thiab kuaj duab yog qhov tseem ceeb txhawm rau txheeb xyuas cov qog nqaij hlav hauv lub cev:

• Ntsuam xyuas ntshav: ntawm kev kuaj ntshav, xav paub txog mastocytosis thiab ntshav tsis txaus. Tshwj xeeb tshaj yog muaj mastocytosis, uas yog tus yam ntxwv ntawm tus txheej txheem no hauv miv.
• Lub plab ultrasound: ultrasound tuaj yeem kuaj pom splenomegaly lossis cov hnyuv loj thiab saib cov metastases hauv cov qog ntshav mesenteric lossis lwm yam kabmob xws li daim siab. Nws tseem tso cai rau koj pom kev hloov pauv ntawm tus po parenchyma lossis nodules.
• xoo hluav taws xob hauv siab: CXR tso cai rau peb soj ntsuam lub xeev ntawm lub ntsws, nrhiav kev nthuav dav, pleural effusion lossis hloov pauv hauv cranial mediastinum.
• Cytology: Kev siv rab koob hnoos hnoos zoo nyob hauv tus po lossis tus hnyuv tuaj yeem sib txawv ntawm cov qog nqaij hlav qog los ntawm lwm cov txheej txheem tau piav qhia hauv kev kuaj mob sib txawv. Yog tias ua tiav hauv cov dej pleural lossis peritoneal, cov qog mast thiab eosinophils tuaj yeem pom.

Kev kho mob qog noj ntshav mast hauv miv

Kev kho mob kom ua raws kuj yuav nthuav qhia qee qhov kev hloov pauv raws li hom qog nqaij hlav qog noj ntshav yuav tsum tau kho.

Kev kho mob ntawm cov qog nqaij hlav qog nqaij hlav hauv cov miv

Kev kho mob qog nqaij hlav qog nqaij hlav cuticle yog ua nrog tshem tawm phais, txawm tias yog cov ntaub ntawv keeb kwm yav dhau los, uas zoo li thim rov qab los ntawm tus kheej.

Kev phais yog kho kom zoo thiab yuav tsum tau ua los ntawm kev tshem tawm hauv ib cheeb tsam, hauv cov neeg mob qog noj ntshav, thiab nrog cov nyom ntau ntxiv hauv cov kis mob. Feem ntau, cov tshem tawm hauv zos nrog cov npoo nruab nrab ntawm 0.5 thiab 1 cm tau hais qhia rau txhua qhov tawv nqaij ntawm cov qog nqaij hlav qog nqaij hlav kuaj pom los ntawm cytology lossis kuaj nqaij.

Kev rov tshwm sim ntawm cov qog nqaij hlav qog nqaij hlav hauv lub cev yog qhov tsawg heev, txawm tias tshem tawm tsis tiav.

Kev kho mob qog nqaij hlav qog noj ntshav hauv cov miv

LUB tshem tawm phais ntawm cov qog nqaij hlav qog nqaij hlav hauv lub cev tau ua hauv miv nrog cov hnyuv loj lossis tus po tsis muaj metastases lwm qhov. Ua ntej tshem tawm, cov siv cov tshuaj antihistamines xws li cimetidine lossis chlorpheramine raug nquahu kom txo qis qhov kev pheej hmoo ntawm mast cell degranulation, uas yuav ua rau muaj teeb meem xws li mob plab zom mov, ua rau lub cev tsis xws luag thiab ua kom lub cev tsis muaj zog.

Lub sijhawm muaj sia nyob nruab nrab tom qab splenectomy yog nruab nrab 12 thiab 19 hli, tab sis qhov tsis zoo tshwm sim muaj xws li miv nrog anorexia, hnyav hnyav, ntshav tsis txaus, mastocythemia, thiab metastasis.

Tom qab phais tas, nws feem ntau yog muab rau ntxiv tshuaj kho mob nrog prednisolone, vinblastine lossis lomustine.

Thaum muaj metastasis lossis kev koom nrog hauv lub cev, qhov ncauj prednisolone tuaj yeem siv tau ntawm 4-8 mg/kg txhua 24-48 teev. Yog tias xav tau tus neeg saib xyuas tshuaj ntxiv, chlorambucil tuaj yeem siv qhov ncauj ntawm qhov koob tshuaj 20 mg/m2 txhua ob lub lis piam.

Txhawm rau txhim kho cov tsos mob ntawm qee tus miv, tshuaj antihistamine txhawm rau txo cov kua qaub ntau dhau, xeev siab thiab muaj kev pheej hmoo ntawm lub plab zom mov, tiv thaiv lub plab, ua kom lub plab zom mov lossis ua kom loog.

Tam sim no koj paub txhua yam txog feline mast cell qog, peb qhia cov vis dis aus hauv qab no hais txog cov kab mob feem ntau hauv miv:

Kab lus no yog rau cov ntaub ntawv xov xwm nkaus xwb, ntawm PeritoAnimal.com.br peb tsis tuaj yeem sau ntawv kho tsiaj los yog ua txhua yam kev kuaj mob. Peb qhia tias koj coj koj tus tsiaj mus rau tus kws kho tsiaj yog tias nws muaj yam mob lossis tsis xis nyob.

Yog tias koj xav nyeem ntau cov ntawv zoo ib yam li Cov qog nqaij hlav loj hauv cov miv - Cov tsos mob, kev kho mob thiab kev kwv yees, peb pom zoo kom koj nkag mus rau Peb Lwm Yam teeb meem kev noj qab haus huv.