Zoo Siab
- Cushing Syndrome yog dab tsi?
- Cushing syndrome hauv dev: ua rau
- Cov tsos mob ntawm Cushing syndrome
- Cushing syndrome: predisposition hauv qee tus dev
- Cushing syndrome: keeb kwm hauv pituitary:
- Cushing syndrome: keeb kwm hauv cov qog adrenal:
- Cushing syndrome: keeb kwm iatrogenic vim muaj kev txwv lossis siv ntau dhau ntawm glucocorticoids thiab lwm yam tshuaj:
- Cushing syndrome: kuaj mob thiab kho mob
Cov dev tau qhia lawv lub neej nrog peb tau ntau txhiab xyoo. Ntau thiab ntau peb muaj cov phooj ywg plaub hauv peb lub tsev, lossis ntau dua ib tus, nrog leej twg peb xav qhia txhua yam. Txawm li cas los xij, peb yuav tsum ua kom zoo ib yam thiab paub txog lub luag haujlwm uas cuam tshuam nrog tus tsiaj uas, raws li kev muaj sia nyob, muaj nws txoj cai. Peb yuav tsum tsis yog tsuas yog puag thiab pub nws xwb tab sis tseem ua tau raws li nws lub cev thiab lub siab xav tau, ob tus menyuam dev thiab cov laus thiab cov laus.
Muaj tseeb, yog tias koj yog tus zoo siab thiab muaj lub luag haujlwm koom nrog koj tus dev, koj twb tau qhia txog qhov mob feem ntau ntawm cov dev. Hauv tsab xov xwm PeritoAnimal tshiab no, peb yuav coj cov ntaub ntawv hais txog tus Cushing's Syndrome hauv dev - Cov tsos mob thiab ua rau, ntxiv rau muab cov ntaub ntawv cuam tshuam ntau ntxiv. Nyeem ntawv txhawm rau kawm paub tias tus mob no cuam tshuam li cas rau peb cov phooj ywg plaub thiab yuav ua dab tsi txog nws.
Cushing Syndrome yog dab tsi?
Cushing's syndrome kuj tseem hu ua hyperadrenocorticism, thiab nws yog kab mob endocrine (hormonal), uas tshwm sim thaum lub cev tsim tawm qib siab ntawm cov tshuaj cortisol raws sijhawm Cortisol yog tsim tawm hauv cov qog adrenal, nyob ze ntawm ob lub raum.
Qib txaus ntawm cortisol pab peb kom peb lub cev teb rau ib qho kev nyuaj siab, pab ua kom lub cev hnyav, kom muaj cov ntaub so ntswg zoo thiab cov tawv nqaij, thiab lwm yam. Ntawm qhov tod tes, thaum lub cev ntsib kev nce hauv cortisol thiab muaj ntau lawm ntau lawm ntawm cov tshuaj no, lub cev tsis muaj zog, thiab lub cev tau raug rau kis mob thiab kab mob, xws li ntshav qab zib mellitus. Cov tshuaj hormones no ntau dhau tuaj yeem ua rau ntau yam kabmob sib txawv, txo qis kev loj hlob thiab kev ua neej zoo ntawm cov tsiaj uas muaj tus kabmob no.
Tsis tas li ntawd, cov tsos mob tau yooj yim tsis meej pem nrog cov uas tshwm sim los ntawm kev laus ib txwm muaj. Qhov no yog vim li cas ntau tus menyuam dev tsis tau kuaj pom tus kab mob cushing syndrome, raws li cov tsos mob tsis pom los ntawm qee tus menyuam dev laus 'tus saib xyuas. Nws yog ib qho tseem ceeb kom kuaj pom cov tsos mob kom sai li sai tau thiab ua txhua qhov kev sim ua kom txog thaum keeb kwm ntawm tus kab mob cushing tau kuaj pom thiab kho sai li sai tau.
Cushing syndrome hauv dev: ua rau
Muaj ntau dua ib qho keeb kwm lossis ua rau cushing syndrome hauv dev. Tshwj xeeb, muaj peb qho ua tau uas tuaj yeem ua rau cortisol ntau lawm ntau lawm:
- Kev ua haujlwm tsis zoo ntawm lub caj pas pituitary lossis pituitary;
- Kev ua haujlwm tsis zoo ntawm cov qog adrenal lossis qog adrenal;
- Iatrogenic keeb kwm, uas tshwm sim thib ob vim kev kho mob nrog glucocorticoids, corticosteroids thiab tshuaj nrog progesterone thiab cov khoom siv, los kho qee yam kab mob hauv dev.
Raws li peb tau hais los lawm, cov qog adrenal tsim cov tshuaj hormone cortisol, yog li cov teeb meem hauv cov qog no tuaj yeem ua rau muaj cov tsos mob cushing. Txawm li cas los xij, cov qog adrenal yog, nyeg, tswj los ntawm cov tshuaj hormones uas tau zais los ntawm cov caj pas pituitary lossis pituitary, nyob hauv lub hlwb. Yog li, teeb meem hauv lub caj pas kuj tseem tuaj yeem ua rau cov qib cortisol khiav tawm ntawm kev tswj hwm. Thaum kawg, muaj cov tshuaj glucocorticoids thiab lwm yam tshuaj uas tau siv los kho qee yam kab mob hauv dev, tab sis yog siv tsis raug, piv txwv li hauv cov xeev txwv tsis pub siv lossis ntau npaum li cas thiab lub sijhawm, lawv tuaj yeem ua rau tsim cov cushing syndrome, vim lawv hloov pauv kev tsim cov cortisol.
Nws tuaj yeem hais tau tias feem ntau yog keeb kwm ntawm cushing syndrome, lossis hyperadrenocorticism, ntawm 80-85% ntawm cov neeg feem ntau yog cov qog lossis ua kom lub siab nyob hauv cov caj pas, uas zais zais qhov ntau ntawm ACTH cov tshuaj hormones, lub luag haujlwm ua rau cov qog adrenal tsim cov cortisol ntau dua li ib txwm. Lwm txoj kev tsawg dua, ntawm 15-20% ntawm cov xwm txheej tshwm sim hauv cov qog adrenal, feem ntau yog vim muaj qog lossis hyperplasia. Iatrogenic keeb kwm yog tsawg dua.
Nws yog ib qho tseem ceeb heev uas ua rau cushing syndrome hauv dev tau kuaj pom sai li sai tau. Tau kawg, tus kws kho tsiaj tshwj xeeb yuav tsum ua qhov no los ntawm kev ua ntau qhov kev sim thiab sau ntawv kho mob uas tsim nyog tshaj plaws uas yuav ua tiav raws qhov ua los lossis keeb kwm ntawm cushing syndrome hauv dev.
Cov tsos mob ntawm Cushing syndrome
Ntau yam ntawm cov tsos mob tuaj yeem tsis meej pem nrog cov tsos mob hnub nyoog hauv cov dev. thiab vim qhov no, ntau tus neeg tsis paub tias cov cim thiab tsos mob uas lawv tus phooj ywg ncaj ncees nthuav tawm yog vim muaj qhov txawv txav hauv kev tsim cov tshuaj cortisol, lossis Cushing's syndrome. Raws li tus kab mob nyhav zuj zus, cov tsos mob tshwm sim me ntsis, thiab nws yuav siv sij hawm ntau lub hlis lossis ntau xyoo rau txhua tus ntawm lawv tshwm sim. Nco ntsoov tias tsis yog txhua tus dev teb tib txoj hauv kev kom nce cortisol, yog li nws muaj peev xwm ua tau tias tsis yog txhua tus dev qhia tib yam tsos mob.
Txawm hais tias muaj lwm tus, tus cov tsos mob mfeem ntau cov tsos mob ntawm cushing syndrome yog raws li nram no:
- Ua kom nqhis dej ntau ntxiv thiab tso zis
- Ua kom qab los noj mov
- Teeb meem ntawm daim tawv nqaij thiab kab mob
- Alopecia
- Daim tawv nqaij hyperpigmentation
- cov plaub hau tsis zoo
- Nquag gasps;
- leeg tsis muaj zog thiab atrophy
- Lub cev tsis muaj zog
- Kev rog nyob hauv plab (lub plab o)
- Ua kom siab me me
- rov kis mob ntawm daim tawv nqaij
- Hauv cov xwm txheej siab ntawm keeb kwm pituitary, kev hloov pauv ntawm lub paj hlwb tshwm sim
- Kev hloov pauv ntawm lub voj voog ntawm poj niam
- Testicular atrophy hauv cov txiv neej
Qee zaum, txoj hauv kev ncaj tshaj plaws ntawm kev paub tias nws yog cushing syndrome tsis yog cov tsos mob, tab sis thaum tus kws kho tsiaj kuaj pom tus kab mob thib ob uas tsim los ntawm tus mob, xws li mob ntshav qab zib mellitus, theem nrab hypothyroidism, tshee thiab hloov pauv tus cwj pwm, ntawm lwm qhov muaj peev xwm.
Cushing syndrome: predisposition hauv qee tus dev
Qhov txawv txav no hauv kev ua haujlwm ntawm cov qog adrenal uas ua rau muaj kev tsim tawm ntau ntawm cortisol ntau dua hauv cov dev laus dua li cov menyuam yaus, feem ntau tshwm sim los ntawm 6 xyoo thiab tshwj xeeb tshaj yog hauv menyuam dev ntau dua 10 xyoo. Nws tseem tuaj yeem cuam tshuam rau cov dev uas muaj kev nyuaj siab los ntawm qee yam lwm yam teeb meem lossis lwm yam xwm txheej cuam tshuam. Zoo li muaj pov thawj xav tias feem ntau ntawm Cushing's syndrome tshwm sim los ntawm pituitary tshwm sim hauv cov dev hnyav dua 20 kg, thaum cov xwm txheej ntawm keeb kwm adrenal ntau zaus hauv cov dev hnyav ntau dua 20 kg, txawm tias hom adrenal kuj tshwm sim hauv me me me me menyuam dev.
Txawm hais tias tus dev kev sib deev tsis cuam tshuam rau qhov tshwm sim ntawm cov tshuaj hormones no, tus tsiaj zoo li muaj qee yam cuam tshuam. Cov no yog qee qhov kev yug me nyuam feem ntau yuav raug kev txom nyem los ntawm cushing syndrome, raws li lub hauv paus ntawm qhov teeb meem:
Cushing syndrome: keeb kwm hauv pituitary:
- Daschshund;
- Poodle;
- Boston terrier;
- Miniature Schnauzer;
- Maltese Bichon;
- Bobtail.
Cushing syndrome: keeb kwm hauv cov qog adrenal:
- Yorkshire terrier;
- Dachshund;
- Poodle me me;
- Tus tswv yug yaj German.
Cushing syndrome: keeb kwm iatrogenic vim muaj kev txwv lossis siv ntau dhau ntawm glucocorticoids thiab lwm yam tshuaj:
- Boxer;
- Xibhwb ntawm Pyrenees;
- Labrador retriever;
- Tsiaj
Cushing syndrome: kuaj mob thiab kho mob
Nws yog ib qho tseem ceeb heev yog tias peb kuaj pom ib qho ntawm cov tsos mob tau tham hauv ntu dhau los, txawm hais tias lawv yuav zoo li cov laus, peb mus rau ntseeg tus kws kho tsiaj los ua qhov kev kuaj mob uas nws pom tias tsim nyog kom txiav tawm lossis kuaj mob cushing syndrome hauv peb cov plaub hau thiab qhia qhov kev daws teeb meem zoo tshaj plaws thiab kev kho mob.
Tus kws kho tsiaj yuav tsum ua ob peb xeem, xws li kuaj ntshav, kuaj zis, kuaj cov tawv nqaij hauv thaj chaw uas qhia pom kev hloov pauv, X-duab hluav taws xob, ntsuas hluav taws xob, ntsuas tshwj xeeb txhawm rau ntsuas qhov siab ntawm cortisol hauv cov ntshav thiab, yog tias koj xav tias muaj keeb kwm hauv lub caj pas, koj yuav tsum ua CT thiab MRI.
Tus kws kho tsiaj yuav tsum sau ntawv qhov kev kho mob tsim nyog tshaj plaws rau cushing syndrome, uas yuav vam khom tag nrhontawm keeb kwm tias tus mob yuav muaj nyob hauv txhua tus dev. Kev kho tuaj yeem yog tshuaj noj rau lub neej lossis txog thaum tus dev tuaj yeem ua phais kom tswj hwm qib cortisol. Kev kho kuj tuaj yeem yog phais ncaj qha kom tshem cov qog lossis daws qhov teeb meem nthuav tawm hauv cov qog, xws li hauv adrenal lossis pituitary. Kev kho mob raws kev siv tshuaj kho mob lossis kho hluav taws xob kuj tseem tuaj yeem txiav txim siab yog tias cov qog nqaij hlav tsis ua haujlwm. Ntawm qhov tod tes, yog tias qhov ua rau tus mob yog los ntawm iatrogenic keeb kwm, nws txaus los tso tseg cov tshuaj ntawm lwm yam kev kho mob uas tau ua thiab yog qhov ua rau mob cushing syndrome.
Nws yog qhov tsim nyog los txiav txim siab ntau lwm yam tsis zoo ntawm tus dev txoj kev noj qab haus huv thiab qhov muaj peev xwm hauv txhua kis los txiav txim siab seb nws puas zoo dua ua raws kev kho lossis lwm yam. Tsis tas li, peb yuav tsum nqa mus ntsib kws kho tsiaj raws sijhawm kom tswj tau qib cortisol thiab kho tshuaj yog tias tsim nyog, nrog rau tswj cov txheej txheem tom qab ua haujlwm.
Kab lus no yog rau cov ntaub ntawv xov xwm nkaus xwb, ntawm PeritoAnimal.com.br peb tsis tuaj yeem sau ntawv kho tsiaj los yog ua txhua yam kev kuaj mob. Peb qhia tias koj coj koj tus tsiaj mus rau tus kws kho tsiaj yog tias nws muaj yam mob lossis tsis xis nyob.